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Analysis of institutional authors

Yin, HongfeiAuthor

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April 21, 2022
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Palladium-Catalyzed Carbonylative Synthesis of 2,3-Disubstituted Chromones

Publicated to: Advanced Synthesis & Catalysis. 358 (3): 466-479 - 2016-02-04 358(3), DOI: 10.1002/adsc.201500858

Authors:

Shen, CR; Li, WF; Yin, HF; Spannenberg, A; Skrydstrup, T; Wu, XF
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Affiliations

Aarhus Univ, Dept Chem, Interdisciplinary Nanosci Ctr iNANO, Ctr Insoluble Prot Struct inSPIN, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark - Author
Univ Rostock eV, Leibniz Inst Katalyse, Albert Einstein Str 29A, D-18059 Rostock, Germany - Author

Abstract

An unexpected palladium-catalyzed carbonylative synthesis of 2,3-disubstituted chromones has been developed. Starting from 2-bromofluoro-benzenes and ketones, the corresponding chromones were produced in good yields. By control experiments, this transformation was found to proceed through a sequential carbonylation/Claisen-Hasse rearrangement/intramolecular nucleophilic aromatic substitution approach (SNAr). More specifically, the reaction sequence started with a palladium-catalyzed carbonylation of the ketone with o-bromo-fluorobenzene to give the vinyl benzoates, which subsequently transformed into 1,3-diketones via a Claisen-Hasse rearrangement. The final products were produced after an intramolecular SNAr reaction of the in situ formed 1,3-diketone.
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Keywords

Alpha-arylationAryl bromidesCarbonylationChromonesClaisen-hasse rearrangementCoupling reactionsDerivativesDiversity-oriented synthesisInternal alkynesKetonesMechanismNucleophilic aromatic substitutionO-iodophenolsPalladium catalystsRearrangement

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Advanced Synthesis & Catalysis due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2016, it was in position 4/59, thus managing to position itself as a Q1 (Primer Cuartil), in the category Chemistry, Organic.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-02-07:

  • WoS: 25
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-02-07:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 8.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 8 (PlumX).
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Denmark; Germany.

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Awards linked to the item

The authors thank the State of Mecklenburg-Vorpommern, the Bundesministerium fur Bildung und Forschung (BMBF), and the Deutsche Forschungsgemeinschaft for financial support. Thanks also go to China Scholarship Council (CSC) for their financial support to C. Shen (No. 201406230040). We also thank Dr. C. Fischer, S. Schareina, and S. Buchholz for their excellent technical and analytical support. We also appreciate the general support from Prof. Matthias Beller.
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