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Analysis of institutional authors

Echavarren Pablos, Antonio M.AuthorLopez, SAuthor

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November 26, 2020
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Gold(I)-catalyzed intramolecular [4+2] cycloadditions of arylalkynes or 1,3-enynes with alkenes: Scope and mechanism

Publicated to: Journal Of The American Chemical Society. 130 (1): 269-279 - 2008-01-09 130(1), DOI: 10.1021/ja075794x

Authors:

Nieto-Oberhuber, Cristina; Perez-Galan, Patricia; Herrero-Gomez, Elena; Lauterbach, Thorsten; Rodriguez, Cristina; Lopez, Salome; Bour, Christophe; Rosellon, Antonio; Cardenas, Diego J; Echavarren, Antonio M
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Affiliations

Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain - Author
Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain - Author

Abstract

The cyclizations of enynes substituted at the alkyne gives products of formal [4+2] cyclization with Au(I) catalysts. 1,8-Dien-3-ynes cyclize by a 5-exo-dig pathway to form hydrinclanes. 1,6-Enynes with an aryl ring at the alkyne give 2,3,9,9a-tetrahydro-1H-cyclopenta[b]naphthalenes by a 5-exo-dig cyclization followed by a Friedel-Crafts-type ring expansion. A 6-endo-dig cyclization is also observed in some cases as a minor process, although in a few cases, this is the major cyclization pathway. In addition to cationic gold complexes bearing bulky biphenyl phosphines, a gold complex with tris(2,6-di-tert-butylphenyl)phosphite is exceptionally reactive as a catalyst for this reaction. This cyclization can also be carried out very efficiently with heating under microwave irradiation. DFT calculations support a stepwise mechanism for the cycloaddition by the initial formation of an anti-cyclopropyl gold(l)-carbene, followed by its opening to form a carbocation stabilized by a pi interaction with the aryl ring, which undergoes a Friedel-Crafts-type reaction.
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Keywords

1-vinylcycloalkenesAlkynesCatalyzed cycloisomerization reactionsComplexesEnyne metathesisGoldIndolesPlatinumSkeletal reorganizationTandem cyclization

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Journal Of The American Chemical Society due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2008, it was in position 7/127, thus managing to position itself as a Q1 (Primer Cuartil), in the category Chemistry, Multidisciplinary.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-01-20:

  • Google Scholar: 296
  • WoS: 223
  • Scopus: 203
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-01-20:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 69.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 69 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 3.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Nieto-Oberhuber, C) and Last Author (Echavarren, AM).

the authors responsible for correspondence tasks have been Perez-Galan, P and Echavarren, AM.

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