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31 de julio de 2025
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Review
Hybrid Gold

Technology Roadmap of Micro/Nanorobots

Publicado en: Acs Nano. 19 (27): 24174-24334 - 2025-06-27 19(27), DOI: 10.1021/acsnano.5c03911

Autores:

Ju, Xiaohui; Chen, Chuanrui; Oral, Cagatay M; Sevim, Semih; Golestanian, Ramin; Sun, Mengmeng; Bouzari, Negin; Lin, Xiankun; Urso, Mario; Nam, Jong Seok; Cho, Yujang; Peng, Xia; Landers, Fabian C; Yang, Shihao; Adibi, Azin; Taz, Nahid; Wittkowski, Raphael; Ahmed, Daniel; Wang, Wei; Magdanz, Veronika; Medina-Sanchez, Mariana; Guix, Maria; Bari, Naimat; Behkam, Bahareh; Kapral, Raymond; Huang, Yaxin; Tang, Jinyao; Wang, Ben; Morozov, Konstantin; Leshansky, Alexander; Abbasi, Sarmad Ahmad; Choi, Hongsoo; Ghosh, Subhadip; Fernandes, Barbara Borges; Battaglia, Giuseppe; Fischer, Peer; Ghosh, Ambarish; Sanchez, Beatriz Jurado; Escarpa, Alberto; Martinet, Quentin; Palacci, Jeremie; Lauga, Eric; Moran, Jeffrey; Ramos-Docampo, Miguel A; Stadler, Brigitte; Restrepo, Ramon Santiago Herrera; Yossifon, Gilad; Nicholas, James D; Ignes-Mullol, Jordi; Puigmarti-Luis, Josep; Liu, Yutong; Zarzar, Lauren D; Shields, C Wyatt; Li, Longqiu; Li, Shanshan; Ma, Xing; Gracias, David H; Velev, Orlin; Sanchez, Samuel; Esplandiu, Maria Jose; Simmchen, Juliane; Lobosco, Antonio; Misra, Sarthak; Wu, Zhiguang; Li, Jinxing; Kuhn, Alexander; Nourhani, Amir; Maric, Tijana; Xiong, Ze; Aghakhani, Amirreza; Mei, Yongfeng; Tu, Yingfeng; Peng, Fei; Diller, Eric; Sakar, Mahmut Selman; Sen, Ayusman; Law, Junhui; Sun, Yu; Pena-Francesch, Abdon; Villa, Katherine; Li, Huaizhi; Fan, Donglei Emma; Liang, Kang; Huang, Tony Jun; Chen, Xiang-Zhong; Tang, Songsong; Zhang, Xueji; Cui, Jizhai; Wang, Hong; Gao, Wei; Bandari, Vineeth Kumar; Schmidt, Oliver G; Wu, Xianghua; Guan, Jianguo; Sitti, Metin; Nelson, Bradley J; Pane, Salvador; Zhang, Li; Shahsavan, Hamed; He, Qiang; Kim, Il-Doo; Wang, Joseph; Pumera, Martin
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Afiliaciones

Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, DK-8000 Aarhus, Denmark - Autor o Coautor
Barcelona Inst Sci & Technol BIST, Inst Bioengineering Catalonia IBEC, Barcelona 08028, Spain - Autor o Coautor
Barcelona Inst Sci & Technol BIST, Inst Chem Res Catalonia ICIQ, E-43007 Tarragona, Spain - Autor o Coautor
Barcelona Inst Sci & Technol, Inst Bioengn Catalunya IBEC, Barcelona 08028, Spain - Autor o Coautor
Basque Fdn Sci, Ikerbasque, Bilbao 48009, Spain - Autor o Coautor
BIST, E-08193 Barcelona, Spain - Autor o Coautor
Brno Univ Technol, Cent European Inst Technol, Brno 61200, Czech Republic - Autor o Coautor
Brno Univ Technol, Cent European Inst Technol, Purkynova 123, Brno 61200, Czech Republic - Autor o Coautor
CALTECH, Div Engn & Appl Sci, Andrew & Peggy Cherng Dept Med Engn, Pasadena, CA 91125 USA - Autor o Coautor
Catalan Inst Res & Adv Studies ICREA, Barcelona 08010, Spain - Autor o Coautor
China Univ Min & Technol, Sch Chem Engn & Technol, Xuzhou 221116, Jiangsu, Peoples R China - Autor o Coautor
Chinese Univ Hong Kong, Chow Yuk Ho Technol Ctr Innovat Med, Shatin, Hong Kong 999077, Peoples R China - Autor o Coautor
Chinese Univ Hong Kong, Dept Mech & Automat Engn, Hong Kong 999077, Peoples R China - Autor o Coautor
Chinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong 999077, Peoples R China - Autor o Coautor
Chinese Univ Hong Kong, Dept Surg, Shatin, Hong Kong 999077, Peoples R China - Autor o Coautor
Chinese Univ Hong Kong, T Stone Robot Inst, Shatin, Hong Kong 999077, Peoples R China - Autor o Coautor
CIC nanoGUNE BRTA, E-20018 Donostia San Sebastian, Spain - Autor o Coautor
CNR IMM, I-95123 Catania, Italy - Autor o Coautor
CSIC, Catalan Inst Nanosci & Nanotechnol ICN2, E-08193 Barcelona, Spain - Autor o Coautor
Ctr Mol Bioengn B CUBE, Chair Micro NanoSyst, D-01307 Dresden, Germany - Autor o Coautor
Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept Robot & Mechatron Engn, Daegu 42988, South Korea - Autor o Coautor
Dalian Univ Technol, Inst Robot & Intelligent Syst, Dalian 116024, Peoples R China - Autor o Coautor
DGIST, DGIST ETH Microrobot Res Ctr, Daegu 42988, South Korea - Autor o Coautor
Duke Univ, Dept Mech Engn & Mat Sci, Durham, NC 27709 USA - Autor o Coautor
Ecole Polytech Fed Lausanne, Inst Engn Mech, CH-1015 Lausanne, Switzerland - Autor o Coautor
ETH, Inst Robot & Intelligent Syst, Multiscale Robot Lab, CH-8092 Zurich, Switzerland - Autor o Coautor
Fudan Univ, Dept Mat Sci, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, Inst Optoelect, Shanghai Frontiers Sci Res Base Intelligent Optoe, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, Int Inst Intelligent Nanorobots & Nanosyst IIINN, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, Int Inst Intelligent Nanorobots & Nanosyst, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, Int Inst Intelligent Nanorobots & Nanosyst, State Key Lab Surface Phys, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, State Key Lab Photovolta Sci & Technol, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, State Key Lab Surface Phys, Dept Mat Sci, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, State Key Lab Surface Phys, Int Inst Intelligent Nanorobots & Nanosyst, Shanghai 200438, Peoples R China - Autor o Coautor
Fudan Univ, Yiwu Res Inst, Yiwu 322000, Zhejiang, Peoples R China - Autor o Coautor
George Mason Univ, Dept Mech Engn, Manassas, VA 20110 USA - Autor o Coautor
Harbin Inst Technol Shenzhen, Sch Integrated Circuits, Sauvage Lab Smart Mat, Shenzhen 518055, Peoples R China - Autor o Coautor
Harbin Inst Technol Shenzhen, Sch Mat Sci & Engn, Shenzhen 518055, Guangdong, Peoples R China - Autor o Coautor
Harbin Inst Technol, Key Lab Microsyst & Microstruct Mfg, Minist Educ, Harbin 150080, Peoples R China - Autor o Coautor
Harbin Inst Technol, Sch Med & Hlth, Harbin 150080, Peoples R China - Autor o Coautor
Harbin Inst Technol, State Key Lab Robot & Syst, Harbin 150080, Peoples R China - Autor o Coautor
Heidelberg Univ, Inst Mol Syst Engn & Adv Mat, D-69120 Heidelberg, Germany - Autor o Coautor
Heidelberg Univ, Max Planck Inst Med Res, D-69120 Heidelberg, Germany - Autor o Coautor
HIT Zhengzhou Res Inst, Lab Sci & Engn Multimodal Prevent & Control Major, Minist Ind & Informat Technol, Zhengzhou 450000, Peoples R China - Autor o Coautor
HIT Zhengzhou Res Inst, Minist Ind & Informat Technol, Key Lab Sci & Engn Multimodal Prevent & Control M, Zhengzhou 450000, Peoples R China - Autor o Coautor
HKU CAS Joint Lab New Mat & Dept Chem, Hong Kong 999077, Peoples R China - Autor o Coautor
Hong Kong Sci Pk, Multi Scale Med Robot Ctr, Shatin, Hong Kong 999077, Peoples R China - Autor o Coautor
Indian Inst Sci, Ctr Nano Sci & Engn, Bangalore 560012, Karnataka, India - Autor o Coautor
Indian Inst Sci, Dept Phys, Bangalore 560012, Karnataka, India - Autor o Coautor
Inst Basic Sci IBS, Ctr Nanomed, Seoul 560012, South Korea - Autor o Coautor
Inst Crit Technol & Appl Sci, Dept Biol Syst Engn, Sch Biomed Engn & Sci, Dept Mech Engn, Blacksburg, VA 24061 USA - Autor o Coautor
Inst Sci & Technol Austria ISTA, A-3400 Klosterneuburg, Austria - Autor o Coautor
Institute for Bioengineering of Catalunya (IBEC), The Barcelona Institute of Science and Technology, Barcelona 08028, Spain. - Autor o Coautor
Johns Hopkins Univ, Dept Chem & Biomol Engn, Baltimore, MD 21218 USA - Autor o Coautor
Koc Univ, Coll Engn, TR-34450 Istanbul, Turkiye - Autor o Coautor
Koc Univ, Sch Med, TR-34450 Istanbul, Turkiye - Autor o Coautor
Korea Adv Inst Sci & Technol KAIST, Dept Mat Sci & Engn, Daejeon 34141, South Korea - Autor o Coautor
Max Planck Inst Dynam & Selforg MPI DS, D-37077 Gottingen, Germany - Autor o Coautor
Max Planck Inst Intelligent Syst, Phys Intelligence Dept, D-70569 Stuttgart, Germany - Autor o Coautor
Michigan State Univ, Dept Biomed Engn, E Lansing, MI 48824 USA - Autor o Coautor
Michigan State Univ, Inst Quantitat Hlth Sci & Engn, E Lansing, MI 48824 USA - Autor o Coautor
Minist Educ, Key Lab Microsyst & Microstruct Mfg, Harbin 15001, Peoples R China - Autor o Coautor
Molecular Bionics. Institute for Bioengineering of Catalonia - Autor o Coautor
Natl Univ Singapore, Dept Biomed Engn, Singapore 117583, Singapore - Autor o Coautor
North Carolina State Univ, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA - Autor o Coautor
Penn State Univ, Dept Chem Engn, University Pk, PA 16802 USA - Autor o Coautor
Penn State Univ, Dept Chem, University Pk, PA 16802 USA - Autor o Coautor
Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA - Autor o Coautor
Penn State Univ, Dept Mat Sci, University Pk, PA 16802 USA - Autor o Coautor
Penn State Univ, Engn & Mat Res Inst, University Pk, PA 16802 USA - Autor o Coautor
Rhein Westfal TH Aachen, Dept Phys, DWI Leibniz Inst Interact Mat, D-52074 Aachen, Germany - Autor o Coautor
Shanghai Clin Res & Trial Ctr, Shanghai 201210, Peoples R China - Autor o Coautor
ShanghaiTech Univ, Sch Biomed Engn, Wireless & Smart Bioelect Lab, Shanghai 201210, Peoples R China - Autor o Coautor
ShanghaiTech Univ, State Key Lab Adv Med Mat & Devices, Shanghai 201210, Peoples R China - Autor o Coautor
Shenzhen Univ, Coll Chem & Environm Engn, Shenzhen 518060, Peoples R China - Autor o Coautor
Shenzhen Univ, Sch Biomed Engn, Hlth Sci Ctr, Guangdong Key Lab Biomed Measurements & Ultrasoun, Shenzhen 518060, Guangdong, Peoples R China - Autor o Coautor
Smart Nano-Bio-Devices. Institute for Bioengineering of Catalonia - Autor o Coautor
Southern Med Univ, Guangdong Prov Key Lab New Drug Screening, Sch Pharmaceut Sci, Guangzhou 510515, Peoples R China - Autor o Coautor
Southern Med Univ, NMPA Key Lab Res & Evaluat Drug Metab, Sch Pharmaceut Sci, Guangzhou 510515, Peoples R China - Autor o Coautor
Sun Yat Sen Univ, Sch Mat Sci & Engn, Guangzhou 510275, Peoples R China - Autor o Coautor
Swiss Fed Inst Technol, Inst Robot & Intelligent Syst, Acoust Robot Syst Lab, CH-8803 Ruschlikon, Switzerland - Autor o Coautor
Swiss Fed Inst Technol, Inst Robot & Intelligent Syst, Multiscale Robot Lab, CH-8092 Zurich, Switzerland - Autor o Coautor
Tech Univ Chemnitz, Res Ctr Mat Architectures & Integrat Nanomembrane, D-09126 Chemnitz, Germany - Autor o Coautor
Tech Univ Denmark, Danish Natl Res Fdn, DK-2800 Lyngby, Denmark - Autor o Coautor
Tech Univ Denmark, Villum Foundat Ctr Intelligent Drug Delivery & Se, Dept Hlth Technol, DK-2800 Lyngby, Denmark - Autor o Coautor
Technion Israel Inst Technol, Dept Chem Engn, IL-32000 Haifa, Israel - Autor o Coautor
Tel Aviv Univ, Dept Biomed Engn, IL-69978 Tel Aviv, Israel - Autor o Coautor
Tel Aviv Univ, Sch Mech Engn, IL-69978 Tel Aviv, Israel - Autor o Coautor
Univ Akron, Dept Mech Engn, Dept Biol, Biomimicry Res & Innovat Ctr BRIC, Akron, OH 44325 USA - Autor o Coautor
Univ Alcala, Chem Res Inst Andres M Del Rio, E-28802 Madrid, Spain - Autor o Coautor
Univ Alcala, Dept Analyt Chem Phys Chem & Chem Engn, E-28802 Alcala De Henares, Spain - Autor o Coautor
Univ Barcelona, Dept Condensed Matter Phys, Barcelona 08028, Spain - Autor o Coautor
Univ Barcelona, Dept Mat Sci & Phys Chem, Barcelona 08028, Spain - Autor o Coautor
Univ Barcelona, Inst Quim Teor & Computac, Dept Ciencia Mat & Quim Fis, Barcelona 08028, Spain - Autor o Coautor
Univ Barcelona, Inst Theoret & Computat Chem, Dept Mat Sci & Phys Chem, Barcelona 08028, Spain - Autor o Coautor
Univ Bordeaux, Bordeaux INP, CNRS, ISM,UMR 5255, F-33607 Pessac, France - Autor o Coautor
Univ Calif San Diego, Aiiso Yufeng Li Family Dept Chem & Nano Engn, La Jolla, CA 92093 USA - Autor o Coautor
Univ Cambridge, Dept Appl Math & Theoret Phys, Ctr Math Sci, Cambridge CB3 0WA, England - Autor o Coautor
Univ Catania, Dipartimento Fis & Astron Ettore Majorana, I-95123 Catania, Italy - Autor o Coautor
Univ Colorado, Dept Chem & Biol Engn, Boulder, CO 80303 USA - Autor o Coautor
Univ Groningen, Dept Biomat & Biomed Technol, Surg Robot Lab, NL-9713 AV Groningen, Netherlands - Autor o Coautor
Univ Hong Kong, Dept Chem, Hong Kong 999077, Peoples R China - Autor o Coautor
Univ Hong Kong, Dept Chem, State Key Lab Synthet Chem, Hong Kong 999077, Peoples R China - Autor o Coautor
Univ Hong Kong, Mat Innovat Inst Life Sci & Energy MILES, Hong Kong 999077, Peoples R China - Autor o Coautor
Univ Med Ctr Groningen, NL-9713 AV Groningen, Netherlands - Autor o Coautor
Univ Michigan, Dept Mat Sci & Engn, Ann Arbor, MI 48109 USA - Autor o Coautor
Univ New South Wales, Australian Ctr NanoMed, Sch Chem Engn, Sydney, NSW 2052, Australia - Autor o Coautor
Univ Oxford, Rudolf Peierls Ctr Theoret Phys, Oxford OX1 3PU, England - Autor o Coautor
Univ Strathclyde, Pure & Appl Chem, Glasgow G1 1BX, Lanark, Scotland - Autor o Coautor
Univ Stuttgart, Inst Biomat & Biomol Syst, D-70569 Stuttgart, Germany - Autor o Coautor
Univ Texas Austin, Chandra Dept Elect & Comp Engn, Austin, TX 78712 USA - Autor o Coautor
Univ Texas Austin, Texas Mat Inst, Mat Sci & Engn Program, Austin, TX 78712 USA - Autor o Coautor
Univ Texas Austin, Walker Dept Mech Engn, Austin, TX 78712 USA - Autor o Coautor
Univ Toronto, Dept Chem, Chem Phys Theory Grp, Toronto, ON M5S 3H6, Canada - Autor o Coautor
Univ Toronto, Dept Comp Sci, Toronto, ON M5S IA1, Canada - Autor o Coautor
Univ Toronto, Dept Elect & Comp Engn, Toronto, ON M5S IA1, Canada - Autor o Coautor
Univ Toronto, Dept Mech & Ind Engn, Toronto, ON M5S 3G8, Canada - Autor o Coautor
Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 1A1, Canada - Autor o Coautor
Univ Toronto, Inst Robot, Toronto, ON M5S 3G8, Canada - Autor o Coautor
Univ Twente, Dept Biomech Engn, Surg Robot Lab, NL-7522 NB Enschede, Netherlands - Autor o Coautor
Univ Waterloo, Dept Chem Engn, Fac Engn, Waterloo, ON N2L 3G1, Canada - Autor o Coautor
Univ Waterloo, Waterloo Inst Nanotechnol, Ctr Bioengn & Biotechnol, Syst Design & Biomed Engn, Waterloo, ON N2L 3G1, Canada - Autor o Coautor
Univ Waterloo, Waterloo Inst Nanotechnol, Inst Polymer Res, Ctr Bioengn & Biotechnol,Dept Chem Engn, Waterloo, ON N2L 3G1, Canada - Autor o Coautor
Univ Waterloo, Waterloo Inst Nanotechnol, Polymer Res Inst, Dept Chem Engn,Ctr Bioengn & Biotechnol, Waterloo, ON N2L 3G1, Canada - Autor o Coautor
Virginia Tech, Dept Mech Engn, Blacksburg, VA 24061 USA - Autor o Coautor
Wuhan Univ Technol, Int Sch Mat Sci & Engn, State Key Lab Adv Technol Mat Synth & Proc, Wuhan 430070, Peoples R China - Autor o Coautor
Yonsei Univ, Adv Sci Inst, Dept Nano Biomed Engn NanoBME, Seoul 03722, South Korea - Autor o Coautor
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Resumen

Inspired by Richard Feynman's 1959 lecture and the 1966 film Fantastic Voyage, the field of micro/nanorobots has evolved from science fiction to reality, with significant advancements in biomedical and environmental applications. Despite the rapid progress, the deployment of functional micro/nanorobots remains limited. This review of the technology roadmap identifies key challenges hindering their widespread use, focusing on propulsion mechanisms, fundamental theoretical aspects, collective behavior, material design, and embodied intelligence. We explore the current state of micro/nanorobot technology, with an emphasis on applications in biomedicine, environmental remediation, analytical sensing, and other industrial technological aspects. Additionally, we analyze issues related to scaling up production, commercialization, and regulatory frameworks that are crucial for transitioning from research to practical applications. We also emphasize the need for interdisciplinary collaboration to address both technical and nontechnical challenges, such as sustainability, ethics, and business considerations. Finally, we propose a roadmap for future research to accelerate the development of micro/nanorobots, positioning them as essential tools for addressing grand challenges and enhancing the quality of life.
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Indicios de calidad

Impacto bibliométrico. Análisis de la aportación y canal de difusión

El trabajo ha sido publicado en la revista ACS Nano debido a la progresión y el buen impacto que ha alcanzado en los últimos años, según la agencia WoS (JCR), se ha convertido en una referencia en su campo. En el año de publicación del trabajo, 2025, se encontraba en la posición 28/461, consiguiendo con ello situarse como revista Q1 (Primer Cuartil), en la categoría Materials Science, Multidisciplinary. Destacable, igualmente, el hecho de que la Revista está posicionada por encima del Percentil 90.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-01:

  • WoS: 20
[+]

Impacto y visibilidad social

Desde la dimensión de Influencia o adopción social, y tomando como base las métricas asociadas a las menciones e interacciones proporcionadas por agencias especializadas en el cálculo de las denominadas “Métricas Alternativas o Sociales”, podemos destacar a fecha 2026-04-01:

  • El uso, desde el ámbito académico evidenciado por el indicador de la agencia Altmetric referido como agregaciones realizadas por el gestor bibliográfico personal Mendeley, nos da un total de: 156.
  • La utilización de esta aportación en marcadores, bifurcaciones de código, añadidos a listas de favoritos para una lectura recurrente, así como visualizaciones generales, indica que alguien está usando la publicación como base de su trabajo actual. Esto puede ser un indicador destacado de futuras citas más formales y académicas. Tal afirmación es avalada por el resultado del indicador “Capture” que arroja un total de: 135 (PlumX).

Con una intencionalidad más de divulgación y orientada a audiencias más generales podemos observar otras puntuaciones más globales como:

  • El Score total de Altmetric: 144.
  • El número de menciones en la red social X (antes Twitter): 36 (Altmetric).
  • El número de menciones en Wikipedia: 2 (Altmetric).
  • El número de menciones en medios de comunicación: 14 (Altmetric).

Es fundamental presentar evidencias que respalden la plena alineación con los principios y directrices institucionales en torno a la Ciencia Abierta y la Conservación y Difusión del Patrimonio Intelectual. Un claro ejemplo de ello es:

  • El trabajo se ha enviado a una revista cuya política editorial permite la publicación en abierto Open Access.
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Análisis de liderazgo de los autores institucionales

Este trabajo se ha realizado con colaboración internacional, concretamente con investigadores de: Australia; Austria; Canada; China; Czech Republic; Denmark; France; Germany; India; Israel; Italy; Netherlands; Republic of Korea; Singapore; Switzerland; Timor-Leste; Turkey; United Kingdom; United States of America.

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Reconocimientos ligados al ítem

The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies. Martin Pumera acknowledges the financial support of Grant Agency of the Czech Republic (EXPRO: 25-15484X). Xiaohui Ju, Xia Peng and Cagatay M. Oral acknowledge ERDF/ESF project TECHSCALE (No. CZ.02.01.01/00/22_008/0004587) for financial support. Xiaohui Ju acknowledges the financial support from Czech Grant Agency GACR standard grant No. 25-15996S. Salvador Pane, Fabian Landers and Semih Sevim acknowledge funding from the European Union's Horizon 2020 Proactive Open program under FETPROACT-EIC-05-2019 ANGIE (No. 952152) and the European Union's Horizon Europe Research and Innovation Programme under the EVA project (GA no. 101047081).Li Zhang acknowledges funding support from the Hong Kong Research Grants Council (RGC) with grant numbers R4015-2, RFS2122-4S03, and STG1/E-401/23-N. Hamed Shahsavan acknowledges Natural Sciences and Engineering Research Council of Canada (NSERC). Cagatay M. Oral and Hamed Shahsavan were in part funded by the WIN-CEITEC BUT Joint Seed Funding Program. Qiang He and Xiankun Lin acknowledge the National Natural Science Foundation of China (22193033, U22A20346) and Heilongjiang Provincial Key R&D Program (2022ZX02C23) for providing financial support. Il-Doo Kim acknowledges the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2024-00435493). Ramin Golestanian acknowledges support from the Max Planck School Matter to Life and the MaxSynBio Consortium which are jointly funded by the Federal Ministry of Education and Research (BMBF) of Germany and the Max Planck Society. Bradley J. Nelson and Semih Sevim acknowledge funding from the Swiss National Science Foundation under SNSF-Sinergia project no. 198643. Raphael Wittkowski is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - 535275785. Daniel Ahmed acknowledges the support provided by the European Research Council, as part of the European Union's Horizon 2020 research and innovation program (grant agreement 853309, SONOBOTS) and Swiss National Science Foundation (SNSF) under the SNSF Project funding MINT 2022 grant agreement No. 213058. Daniel Ahmed also extends thanks to Zhiyuan Zhang, Mahmoud Medany, and Prajwal Agrawal for helpful discussions. Wei Wang acknowledges the National Natural Science Foundation of China (T2322006) and the Shenzhen Science and Technology Program (RCYX20210609103122038). Mariana Medina-Sanchez acknowledges the financial support received from the European Union's Horizon 2020 research and innovation program (ERC Starting Grant Nr. 853609), the HORIZON-MSCA-2022-COFUND-101126600-SmartBRAIN3, and the Grant PID2023-148899OA-I00 funded by MICIU/AEI/ 10.13039/501100011033. Maria Guix acknowledges the financial support from the Spanish Ministry of Science (grants RYC2020-945030119-I and PID2023-151682NA-I00 funded by MCIN/AEI/10.13039/501100011033/ and FEDER) and Unidades de Excelencia Maria de Maeztu 2021 CEX2021-001202-M. Bahareh Behkam and Naimat Kalim Bari acknowledge support from the National Science Foundation (CBET-2318093). Naimat Kalim Bari also gratefully acknowledges financial support from the Virginia Tech Presidential Postdoctoral Fellowship. Raymond Kapral acknowledges the Natural Sciences and Engineering Research Council of Canada. Giuseppe Battaglia, Subhadip Ghosh and Barbara Borges Fernandes thank the European Research Council ChessTaG grant 769798 (G.B.); Ministry of Science and Innovation of Spain, Proyectos I+D+I PID2020-119914RBI00 and Proyectos I+D+I PID2023-149206OB-I00 and the Agencia de Gestion de Ayudas Universitarias y de Investigacion (AGAUR) for the grant SGR 01538 and for SG fellowship (2022 BP 00214). Alexander Leshansky and Konstantin Morozov acknowledge the support of the Israel Science Foundation (ISF) via grant no. 2899/21. Alberto Escarpa and Beatriz Jurado Sanchez acknowledge support from The Spanish Ministry of Science, Innovation and Universities [Grant PID2023-152298NB-I00 funded by MCIN/AEI/10.13039/501100011033 and FEDER, UE (A.E, B. J. S), grant TED2021-132720B-I00, funded by MCIN/AEI/10.13039/501100011033 and the European Union "NextGenerationEU"/PRTR (A.E, B. J. S); grant CNS2023-144653 funded by MCIN/AEI/10.13039/ 501100011033 and the European Union "NextGenerationEU"/PRTR] and Junta de Comunidades de Castilla la Mancha (grant number SBPLY/23/180225/000058). Jeremie Palacci acknowledges support from the European Union through ERC grant (VULCAN, 101086998). Josep Puigmarti-Luis acknowledges the Agencia Estatal de Investigacion (AEI) for the Maria de Maeztu, project no. CEX2021-001202-M, the Ministerio de Ciencia, Innovacion y Universidades (Grant No. PID2020-116612RB-C33 funded by MCIN/AEI/10.13039/501100011033) and the Generalitat de Catalunya (2021 SGR 00270). James D. Nicholas, Jordi Ignes-Mullol, and Josep Puigmarti-Luis acknowledge support from the European Union's Horizon Europe Research and Innovation Programme under the EVA project (GA no: 101047081). Josep Puigmarti-Luis and Jordi Ignes-Mullol acknowledge support from the European Union's Horizon 2020 Proactive Open program under FETPROACT-EIC-05-2019 ANGIE (No. 952152). Jordi Ignes-Mullol also acknowledges the Ministerio de Ciencia, Innovacion y Universidades (Grant No. PID2022-137713NB-C21 funded by MICIU/AEI/10.13039/501100011033). Lauren Zarzar and Yutong Liu acknowledge support from the US Army Research Office (Grant W911NF-18-1-0414). Longqiu Li acknowledges the National Natural Science Foundation of China (52125505, U23A20637) for providing financial support. Wyatt Shields acknowledges support from the National Science Foundation (NSF) through a CAREER grant (CBET 2143419). Xing Ma acknowledges the support from Shenzhen Science and Technology Program (RCJC20231211090000001). David H. Gracias acknowledges support from the NIH-NIBIB (R01EB017742). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Samuel Sanchez acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 and Horizon Europe research and innovation programmes (grants agreement No 866348, i-NanoSwarms), the CERCA program by the Generalitat de Catalunya, the project 2021 SGR 01606, and the "Centro de Excelencia Severo Ochoa" (Grant CEX2023-001282-S). Maria Jose Esplandiu acknowledges the Ministerio de Ciencia e Innovacion of Spain (MICIN) through PID 2021-124568NB-I00 and TED2021-129898B-C21 project. Sarthak Misra and Antonio Lobosco acknowledge funding from European Research Council (ERC) under the European Union's Horizon 2020 Research and Innovation Programme (Grant Nr. 866494, project-MAESTRO). Jinxing Li acknowledges support from the National Science Foundation under Award Nos. CMMI 2323917, ECCS-2216131, ECCS 2339495, ECCS-2334134, NIH NIBIB Trailblazer R21 Award, and Henry Ford Hospital + MSU Cancer Research Pilot Award.Ze Xiong acknowledges the financial support from the International S&T Cooperation Program of Shanghai (24490710900) and the start-up grant from ShanghaiTech University (2023F0209-000-02). Yongfeng Mei acknowledges the National Natural Science Foundation of China (62375054), Science and Technology Commission of Shanghai Municipality (24520750200, 24CL2900200), and Shanghai Talent Programs. Ayusman Sen thanks the National Science Foundation, the Air Force Office of Scientific Research, and the Sloan Foundation for their financial support. Abdon Pena-Francesch acknowledges support from the Air Force Office of Scientific Research under award number FA9550-24-1-0185. Katherine Villa acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (GA no. 101076680; PhotoSwim) and the support from the Spanish Ministry of Science (MCIN/AEI/10.13039/501100011033) and the European Union (Next generation EU/PRTR) through the Ramon y Cajal grant, RYC2021-031075-I. Kang Liang acknowledges support from the Australian Research Council (DP250101401 and FT220100479) and the National Breast Cancer Foundation, Australia (IIRS-22-104). Jizhai Cui acknowledges the National Key Technologies R&D Program of China (2022YFA1207000) and Shanghai Rising-Star Program (24QA2700700). Xiang-Zhong Chen acknowledges the National Natural Science Foundation of China (52473254) and the National Key Research and Development Program of China (2023YFB35070003).
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